CD47 as a Potential Target to Therapy for Infectious Diseases

CD47 as a Potential Target to Therapy for Infectious Diseases

The integrin associated protein (CD47) is a widely and moderately expressed glycoprotein in all healthy cells. Cancer cells are known to induce increased CD47 expression. Similar to cancer cells, all immune cells can upregulate their CD47 surface expression during infection. The CD47-SIRPa interacti...

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Bibliographic Details
Main Authors: Lamin B. Cham, Tom Adomati, Fanghui Li, Murtaza Ali, Karl S. Lang
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Antibodies
Subjects:
anti-CD47
macrophages
dendritic cells
T cells
therapy
viral infection
Online Access:https://www.mdpi.com/2073-4468/9/3/44

Internet

https://www.mdpi.com/2073-4468/9/3/44

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