IGF-IR internalizes with Caveolin-1 and PTRF/Cavin in HaCat cells.

IGF-IR internalizes with Caveolin-1 and PTRF/Cavin in HaCat cells.

BACKGROUND:Insulin-like growth factor-I receptor (IGF-IR) is a tyrosine kinase receptor (RTK) associated with caveolae, invaginations of the plasma membrane that regulate vesicular transport, endocytosis and intracellular signaling. IGF-IR internalization represents a key mechanism of down-modulatio...

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Bibliographic Details
Main Authors: Barbara Salani, Mario Passalacqua, Sara Maffioli, Lucia Briatore, Meriem Hamoudane, Paola Contini, Renzo Cordera, Davide Maggi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2994771?pdf=render

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http://europepmc.org/articles/PMC2994771?pdf=render

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