[Mn(PaPy2Q)(NO)]ClO4, a Near-Infrared Light activated release of Nitric Oxide drug as a nitric oxide donor for therapy of human prostate cancer cells in vitro and in vivo

[Mn(PaPy2Q)(NO)]ClO4, a Near-Infrared Light activated release of Nitric Oxide drug as a nitric oxide donor for therapy of human prostate cancer cells in vitro and in vivo

This study was the first to investigate the synthesis of near-infrared light-sensitive NO prodrug [Mn(PaPy2Q)(NO)]ClO4, and detection the amount of NO released by the drug in different time and near infrared light (10 mW, 20 mW). It showed that with the increase of light power, the time required for...

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Bibliographic Details
Main Authors: Yuwan Zhao, Zhuo Li, Huancheng Tang, Shanhong Lin, Wenfeng Zeng, Dongcai Ye, Xin Zeng, Qiuming Luo, Jianwei Li, Zhixian Ao, Jierong Mo, Lixin Chen, Yiqiu Yang, Yunsheng Huang, Jianjun Liu
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Prostate cancer
NO prodrug
Near-infrared light sensitive
Nude mouse xenograft
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332221001736

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http://www.sciencedirect.com/science/article/pii/S0753332221001736

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