Metabolomics analysis of human acute graft-versus-host disease reveals changes in host and microbiota-derived metabolites

Metabolomics analysis of human acute graft-versus-host disease reveals changes in host and microbiota-derived metabolites

Graft versus host disease (GvHD) still hinders allogeneic hematopoietic stem cell transplantation. Here, the authors use metabolomics to analyze two cohorts of paired transplant recipients and donors, identifying significant differences in both host- and microbiota-derived metabolites.

Bibliographic Details
Main Authors: David Michonneau, Eleonora Latis, Emmanuel Curis, Laetitia Dubouchet, Sivapriya Ramamoorthy, Brian Ingram, Régis Peffault de Latour, Marie Robin, Flore Sicre de Fontbrune, Sylvie Chevret, Lars Rogge, Gérard Socié
Format: Article
Language:English
Published: Nature Publishing Group 2019-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13498-3

Internet

https://doi.org/10.1038/s41467-019-13498-3

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