YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas

YAP manipulates proliferation via PTEN/AKT/mTOR-mediated autophagy in lung adenocarcinomas

Abstract Background Autophagy is a double-edged sword during the initiation and progression of multiple tumors. The Hippo pathway effector YAP has been proved to be involved in autophagy processes. The present study aimed to investigate how YAP regulates cell proliferation via autophagy in lung aden...

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Bibliographic Details
Main Authors: Wei Xu, Mingjiong Zhang, Yue Li, Yu Wang, Kai Wang, Qiaoyu Chen, Runjie Zhang, Weiwei Song, Qiqing Huang, Weihong Zhao, Jianqing Wu
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Cancer Cell International
Subjects:
LUADs
YAP
PTEN/AKT/mTOR
Autophagy
Online Access:https://doi.org/10.1186/s12935-020-01688-9

Internet

https://doi.org/10.1186/s12935-020-01688-9

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