Prolonged Excretion of Poliovirus among Individuals with Primary Immunodeficiency Disorder: An Analysis of the World Health Organization Registry

Prolonged Excretion of Poliovirus among Individuals with Primary Immunodeficiency Disorder: An Analysis of the World Health Organization Registry

Individuals with primary immunodeficiency disorder may excrete poliovirus for extended periods and will constitute the only remaining reservoir of virus after eradication and withdrawal of oral poliovirus vaccine. Here, we analyzed the epidemiology of prolonged and chronic immunodeficiency-related v...

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Main Authors: Grace Macklin, Yi Liao, Marina Takane, Kathleen Dooling, Stuart Gilmour, Ondrej Mach, Olen M. Kew, Roland W. Sutter, The iVDPV Working Group, Ousmane Diop, Nicksy Gumede Moeletsi, Raffaella Williams, Mohamed Seghier, Francis Delpeyroux, Gloria Rey Benito, Maria Cecilia Freire, Cara Burns, Humayun Asghar, Salman Sharif, Jagadish Deshpande, Shohreh Shahmahmoodi, Henda Triki, Laila E Bassioni, Amina Al-Jardani, Eugene Merav Weil Gavrilin, Javier Martín, Sirima Pattamadilok, Sunethra Gunasena, Yan Zhang, Wenbo Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
polio eradication
primary immunodeficiency
vaccine-derived poliovirus
oral poliovirus vaccine
immunodeficiency-related vaccine-derived poliovirus
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01103/full

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http://journal.frontiersin.org/article/10.3389/fimmu.2017.01103/full

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