Monitoring Group Activity of Hamsters and Mice as a Novel Tool to Evaluate COVID-19 Progression, Convalescence, and rVSV-ΔG-Spike Vaccination Efficacy

The COVID-19 pandemic initiated a worldwide race toward the development of treatments and vaccines. Small animal models included the Syrian golden hamster and the K18-hACE2 mice infected with SARS-CoV-2 to display a disease state with some aspects of human COVID-19. A group activity of animals in th...

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Main Authors: Sharon Melamed, Boaz Politi, Ettie Grauer, Hagit Achdout, Moshe Aftalion, David Gur, Hadas Tamir, Yfat Yahalom-Ronen, Shlomy Maimon, Efi Yitzhak, Shay Weiss, Amir Rosner, Noam Erez, Shmuel Yitzhaki, Shmuel C Shapira, Nir Paran, Emanuelle Mamroud, Yaron Vagima, Tomer Israely
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2021.737627/full