Preclinical demonstration of synergistic Active Nutrients/Drug (AND) combination as a potential treatment for malignant pleural mesothelioma.

Preclinical demonstration of synergistic Active Nutrients/Drug (AND) combination as a potential treatment for malignant pleural mesothelioma.

Malignant pleural mesothelioma (MPM) is a poor prognosis disease lacking adequate therapy. We have previously shown that ascorbic acid administration is toxic to MPM cells. Here we evaluated a new combined therapy consisting of ascorbate/epigallocatechin-3-gallate/gemcitabine mixture (called AND, fo...

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Bibliographic Details
Main Authors: Viviana Volta, Elia Ranzato, Simona Martinotti, Simone Gallo, Maria Veronica Russo, Luciano Mutti, Stefano Biffo, Bruno Burlando
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3590277?pdf=render

Internet

http://europepmc.org/articles/PMC3590277?pdf=render

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