In Vitro Modeling of Human Germ Cell Development Using Pluripotent Stem Cells

In Vitro Modeling of Human Germ Cell Development Using Pluripotent Stem Cells

Summary: Due to differences across species, the mechanisms of cell fate decisions determined in mice cannot be readily extrapolated to humans. In this study, we developed a feeder- and xeno-free culture protocol that efficiently induced human pluripotent stem cells (iPSCs) into PLZF+/GPR125+/CD90+ s...

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Bibliographic Details
Main Authors: Yuncheng Zhao, Shicheng Ye, Dongli Liang, Pengxiang Wang, Jing Fu, Qing Ma, Ruijiao Kong, Linghong Shi, Xueping Gong, Wei Chen, Wubin Ding, Wenjing Yang, Zijue Zhu, Huixing Chen, Xiaoxi Sun, Jun Zhu, Zheng Li, Yuan Wang
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671118300274

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http://www.sciencedirect.com/science/article/pii/S2213671118300274

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