CD200 promotes immunosuppression in the pancreatic tumor microenvironment

Background A significant challenge to overcome in pancreatic ductal adenocarcinoma (PDAC) is the profound systemic immunosuppression that renders this disease non-responsive to immunotherapy. Our supporting data provide evidence that CD200, a regulator of myeloid cell activity, is expressed in the P...

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Bibliographic Details
Main Authors: Brooke Benner, Terence M Williams, Fouad Choueiry, Molly Torok, Kriti Agrawal, Anna Deems, Alice Hinton, Jami Shaffer, Bradley W Blaser, Anne M Noonan, Darwin L Conwell, Phil A Hart, Zobeida Cruz-Monserrate, Xue-Feng Bai, William E Carson III
Format: Article
Language:English
Published: BMJ Publishing Group 2020-06-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/1/e000189.full