Estimating the Relative Biological Effectiveness of Auger Electron Emitter 123I in Human Lymphocytes

Estimating the Relative Biological Effectiveness of Auger Electron Emitter 123I in Human Lymphocytes

Auger electron emitters are considered to be a promising strategy for targeted radionuclide therapy of metastatic diseases, given their high linear energy transfer (LET) and short range in tissue which could potentially limit normal tissue toxicity. Particularly Auger electron emitters that can be t...

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Bibliographic Details
Main Authors: Hein Fourie, Shankari Nair, Xanthene Miles, Daniel Rossouw, Philip Beukes, Richard T. Newman, Jan Rijn Zeevaart, Charlot Vandevoorde, Jacobus Slabbert
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Physics
Subjects:
iododeoxyuridine
auger electron
123I
micronucleus assay
relative biological effectiveness
GEANT4 Monte Carlo simulations
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2020.567732/full

Internet

https://www.frontiersin.org/articles/10.3389/fphy.2020.567732/full

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