The antioxidant effects of riluzole on the APRE-19 cell model injury-induced by t-BHP

The antioxidant effects of riluzole on the APRE-19 cell model injury-induced by t-BHP

Abstract Background Age-related macular degeneration (AMD) causes the dysfunction of the retinal pigment epithelial (RPE) cells. In this study, we examined the effects of riluzole, a sustained activator of the TRAAK potassium channel, on human RPE (ARPE-19) cells in an oxidant-induced cell-injury mo...

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Bibliographic Details
Main Authors: Chaolan Shen, Wei Ma, Wenbin Zheng, Hao Huang, Renchun Xia, Chu Li, Xiaobo Zhu
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Ophthalmology
Subjects:
Riluzole
TRAAK K2P channel
ARPE-19 cells
AMD
apoptosis
Online Access:http://link.springer.com/article/10.1186/s12886-017-0614-0

Internet

http://link.springer.com/article/10.1186/s12886-017-0614-0

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