A suboptimal 5' splice site downstream of HIV-1 splice site A1 is required for unspliced viral mRNA accumulation and efficient virus replication
<p>Abstract</p> <p>Background</p> <p>Inefficient alternative splicing of the human immunodeficiency virus type 1(HIV-1) primary RNA transcript results in greater than half of all viral mRNA remaining unspliced. Regulation of HIV-1 alternative splicing occurs through the...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-02-01
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| Series: | Retrovirology |
| Online Access: | http://www.retrovirology.com/content/3/1/10 |