Biosynthesis of 5α-cholestan-3β-ol in rat and guinea pig liver in vitro

The in vitro conversion of dl-mevalonate-2-C14 and cholesterol-4-C14 to 5α-cholestan-3β-ol was studied in liver homogenates of rats and guinea pigs. On the average 0.01–0.05% of the substrate radioactivity was converted to 5α-cholestan-3β-ol by the livers of both species during the 4 hr incubation p...

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Bibliographic Details
Main Authors: Sarah Shefer, Susan Milch, Erwin H. Mosbach
Format: Article
Language:English
Published: Elsevier 1965-01-01
Series:Journal of Lipid Research
Subjects:
rat
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752039636X