Enhancing the in vitro and in vivo activity of itraconazole against breast cancer using miltefosine-modified lipid nanocapsules

Enhancing the in vitro and in vivo activity of itraconazole against breast cancer using miltefosine-modified lipid nanocapsules

Itraconazole (ITC), a well-tolerated antifungal drug, exerts multiple anticancer effects which justified its preclinical and clinical investigation as potential anti-cancer agent with reduced side effects. Enhancement of ITC anti-cancer efficacy would bring valuable benefits to patients. We propose...

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Bibliographic Details
Main Authors: Nabila A. El-Sheridy, Riham M. El-Moslemany, Alyaa A. Ramadan, Maged W. Helmy, Labiba K. El-Khordagui
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Drug Delivery
Subjects:
itraconazole
miltefosine
lipid nanocapsules
breast cancer
mcf-7 cells
ehrlich tumor
biomarkers
Online Access:http://dx.doi.org/10.1080/10717544.2021.1917728

Internet

http://dx.doi.org/10.1080/10717544.2021.1917728

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