A Review of Study Designs and Statistical Methods for Genomic Epidemiology Studies using Next Generation Sequencing

A Review of Study Designs and Statistical Methods for Genomic Epidemiology Studies using Next Generation Sequencing

Results from numerous linkage and association studies have greatly deepened scientists’ understanding of the genetic basis of many human diseases, yet some important questions remain unanswered. For example, although a large number of disease-associated loci have been identified from genome-wide ass...

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Bibliographic Details
Main Authors: Qian eWang, Qiongshi eLu, Hongyu eZhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Genetics
Subjects:
Next-generation sequencing
statistical methods
Study Design
Genomic epidemiology
Genetic etiology
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00149/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2015.00149/full

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