Development of Store-Operated Calcium Entry-Targeted Compounds in Cancer

Store-operated Ca2+ entry (SOCE) is the major pathway of Ca2+ entry in mammalian cells, and regulates a variety of cellular functions including proliferation, motility, apoptosis, and death. Accumulating evidence has indicated that augmented SOCE is related to the generation and development of cance...

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Bibliographic Details
Main Authors: Xiaojing Liang, Ningxia Zhang, Hongming Pan, Jiansheng Xie, Weidong Han
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.688244/full