Potent Antifungal Properties of Dimeric Acylphloroglucinols from <i>Hypericum mexicanum</i> and Mechanism of Action of a Highly Active 3′Prenyl Uliginosin B

Potent Antifungal Properties of Dimeric Acylphloroglucinols from <i>Hypericum mexicanum</i> and Mechanism of Action of a Highly Active 3′Prenyl Uliginosin B

The success of antifungal therapies is often hindered by the limited number of available drugs. To close the gap in the antifungal pipeline, the search of novel leads is of primary importance, and here the exploration of neglected plants has great promise for the discovery of new principles. Through...

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Bibliographic Details
Main Authors: Noemi Tocci, Tobias Weil, Daniele Perenzoni, Marco Moretto, Nicolai Nürk, Santiago Madriñán, Ruggero Ferrazza, Graziano Guella, Fulvio Mattivi
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Metabolites
Subjects:
<i>Hypericum</i>
bioactive compounds
antifungal activity
acylphloroglucinols
structural annotation
nuclear magnetic resonance spectroscopy
Online Access:https://www.mdpi.com/2218-1989/10/11/459

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https://www.mdpi.com/2218-1989/10/11/459

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