Drug-Primed Reinstatement of Cocaine Seeking in Mice: Increased Excitability of Medium-Sized Spiny Neurons in the Nucleus Accumbens

To examine the mechanisms of drug relapse, we first established a model for cocaine IVSA (intravenous self-administration) in mice, and subsequently examined electrophysiological alterations of MSNs (medium-sized spiny neurons) in the NAc (nucleus accumbens) before and after acute application of coc...

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Bibliographic Details
Main Authors: Yao-Ying Ma, Sandy M. Henley, Jeff Toll, James D. Jentsch, Christopher J. Evans, Michael S. Levine, Carlos Cepeda
Format: Article
Language:English
Published: SAGE Publishing 2013-09-01
Series:ASN Neuro
Online Access:https://doi.org/10.1042/AN20130015