Drug-Primed Reinstatement of Cocaine Seeking in Mice: Increased Excitability of Medium-Sized Spiny Neurons in the Nucleus Accumbens
To examine the mechanisms of drug relapse, we first established a model for cocaine IVSA (intravenous self-administration) in mice, and subsequently examined electrophysiological alterations of MSNs (medium-sized spiny neurons) in the NAc (nucleus accumbens) before and after acute application of coc...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2013-09-01
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Series: | ASN Neuro |
Online Access: | https://doi.org/10.1042/AN20130015 |