Role of acetyl-phosphate in activation of the Rrp2-RpoN-RpoS pathway in Borrelia burgdorferi.

Borrelia burgdorferi, the Lyme disease spirochete, dramatically alters its transcriptome and proteome as it cycles between the arthropod vector and mammalian host. During this enzootic cycle, a novel regulatory network, the Rrp2-RpoN-RpoS pathway (also known as the σ(54)-σ(S) sigma factor cascade),...

Full description

Bibliographic Details
Main Authors: Haijun Xu, Melissa J Caimano, Tao Lin, Ming He, Justin D Radolf, Steven J Norris, Frank Gherardini, Alan J Wolfe, X Frank Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2940757?pdf=render