Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction

Integrative transcriptomic analysis of tissue-specific metabolic crosstalk after myocardial infarction

Myocardial infarction (MI) promotes a range of systemic effects, many of which are unknown. Here, we investigated the alterations associated with MI progression in heart and other metabolically active tissues (liver, skeletal muscle, and adipose) in a mouse model of MI (induced by ligating the left...

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Bibliographic Details
Main Authors: Muhammad Arif, Martina Klevstig, Rui Benfeitas, Stephen Doran, Hasan Turkez, Mathias Uhlén, Maryam Clausen, Johannes Wikström, Damla Etal, Cheng Zhang, Malin Levin, Adil Mardinoglu, Jan Boren
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-05-01
Series:eLife
Subjects:
Systems biology
network analysis
whole-body modelling
myocardial infarction
multi-tissue
metabolically active tissues
Online Access:https://elifesciences.org/articles/66921

Internet

https://elifesciences.org/articles/66921

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