Commensal and Pathogenic Biofilms Alter Toll-Like Receptor Signaling in Reconstructed Human Gingiva

Commensal and Pathogenic Biofilms Alter Toll-Like Receptor Signaling in Reconstructed Human Gingiva

The balance between the host and microbe is pivotal for oral health. A dysbiotic oral microbiome and the subsequent host inflammatory response are causes for the most common dental problems, such as periodontitis and caries. Classically, toll-like receptors (TLRs) are known to play important roles i...

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Bibliographic Details
Main Authors: Lin Shang, Dongmei Deng, Jeroen Kees Buskermolen, Sanne Roffel, Marleen Marga Janus, Bastiaan Philip Krom, Wim Crielaard, Susan Gibbs
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
TLR
gingiva
organotypic 3D culture
innate immunity
biofilm
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00282/full

Internet

https://www.frontiersin.org/article/10.3389/fcimb.2019.00282/full

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