Targeted methods for epigenetic age predictions in mice

Abstract Age-associated DNA methylation reflects aspect of biological aging—therefore epigenetic clocks for mice can elucidate how the aging process in this model organism is affected by specific treatments or genetic background. Initially, age-predictors for mice were trained for genome-wide DNA me...

Full description

Bibliographic Details
Main Authors: Yang Han, Miloš Nikolić, Michael Gobs, Julia Franzen, Gerald de Haan, Hartmut Geiger, Wolfgang Wagner
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-79509-2