TMEM175 mediates Lysosomal function and participates in neuronal injury induced by cerebral ischemia-reperfusion

Abstract As the main organelles for the clearance of damaged proteins and damaged organelles, the function of lysosomes is crucial for maintaining the intracellular homeostasis of long-lived neurons. A stable acidic environment is essential for lysosomes to perform their functions. TMEM175 has been...

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Bibliographic Details
Main Authors: Mengling Zhang, Haifeng Lu, Xueshun Xie, Haitao Shen, Xiang Li, Yunhai Zhang, Jiang Wu, Jianqiang Ni, Haiying Li, Gang Chen
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Molecular Brain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13041-020-00651-z