Experimental evidence for the involvement of PDLIM5 in mood disorders in hetero knockout mice.

BACKGROUND: Reports indicate that PDLIM5 is involved in mood disorders. The PDLIM5 (PDZ and LIM domain 5) gene has been genetically associated with mood disorders; it's expression is upregulated in the postmortem brains of patients with bipolar disorder and downregulated in the peripheral lymph...

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Bibliographic Details
Main Authors: Yasue Horiuchi, Maya Ishikawa, Nobuko Kaito, Yoshimi Iijima, Yoshiko Tanabe, Hiroki Ishiguro, Tadao Arinami
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3620230?pdf=render