Inhibition by Zn2+ of A-form Monoamine Oxidase in Monkey Brain Mitochondria
The effects of ZnSO4 on mitochondrial monoamine oxidase (MAO) activity in monkey brain were compared with those in rat and rabbit, in vitro. After preincubation at 25°C for 20 min with 1 μM ZnSO4, MAO-A activity in monkey brain was about 50% using serotonin (5-HT) as a substrate, and the inhibition...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2003-01-01
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Series: | Journal of Pharmacological Sciences |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319327392 |