Permeability changes of integrin-containing multivesicular structures triggered by picornavirus entry.

Cellular uptake of clustered α2β1-integrin induces the formation of membrane compartments that subsequently mature into a multivesicular body (MVB). Enhanced internalization mediated by clustered integrins was observed upon infection by the picornavirus echovirus 1 (EVI). We elucidated the structura...

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Bibliographic Details
Main Authors: Pan Soonsawad, Lassi Paavolainen, Paula Upla, Wattana Weerachatyanukul, Nina Rintanen, Juan Espinoza, Gregory McNerney, Varpu Marjomäki, R Holland Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4191987?pdf=render