The clinicopathological and prognostic impact of 14-3-3 sigma expression on vulvar squamous cell carcinomas
<p>Abstract</p> <p>Background</p> <p>14-3-3 sigma (σ) promotes G2/M cell cycle arrest by sequestering cyclin B1-CDC2 complex in cytoplasm. Down-regulation of 14-3-3σ, which has been demonstrated in various carcinomas, may contribute to malignant transformation. However,...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-10-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/8/308 |