The clinicopathological and prognostic impact of 14-3-3 sigma expression on vulvar squamous cell carcinomas

<p>Abstract</p> <p>Background</p> <p>14-3-3 sigma (σ) promotes G2/M cell cycle arrest by sequestering cyclin B1-CDC2 complex in cytoplasm. Down-regulation of 14-3-3σ, which has been demonstrated in various carcinomas, may contribute to malignant transformation. However,...

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Bibliographic Details
Main Authors: Suo Zhenhe, Tropè Claes G, Wang Zhihui, Trøen Gunhild, Yang Guanrui, Nesland Jahn M, Holm Ruth
Format: Article
Language:English
Published: BMC 2008-10-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/8/308