Crystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureus

Crystal structure of the capsular polysaccharide synthesizing protein CapE of Staphylococcus aureus

Enzymes synthesizing the bacterial CP (capsular polysaccharide) are attractive antimicrobial targets. However, we lack critical information about the structure and mechanism of many of them. In an effort to reduce that gap, we have determined three different crystal structures of the enzyme CapE of...

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Bibliographic Details
Main Authors: Takamitsu Miyafusa, Jose M. M. Caaveiro, Yoshikazu Tanaka, Martin E. Tanner, Kouhei Tsumoto
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2013-06-01
Series:Bioscience Reports
Subjects:
capsular polysaccharide
conformational change
pathogenic bacterium
SDR enzyme
UDP–sugar
X–ray crystallography
Online Access:http://www.bioscirep.org/bsr/033/e043/bsr033e043.htm

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http://www.bioscirep.org/bsr/033/e043/bsr033e043.htm

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