Regulation of Ptch1 by miR-342-5p and FoxO3 Induced Autophagy Involved in Renal Fibrosis

Regulation of Ptch1 by miR-342-5p and FoxO3 Induced Autophagy Involved in Renal Fibrosis

The pathogenesis of renal fibrosis (RF) is not well understood. Here, we performed an integrative database analysis of miRNAs and mRNAs to discover the major regulatory pathway in RF. Putative miRNAs and mRNAs involved in RF in unilateral ureteral obstruction (UUO) model mice were extracted and anal...

Full description

Bibliographic Details
Main Authors: Simin Tang, Yi Wang, Guiling Xie, Wenjun Li, Yanna Chen, Jinshu Liang, Pei Liu, Fuhu Song, Jun Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
renal fibrosis
Ptch1
miR-342-5p
FOXO3
bioinformatics
autophagy
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2020.583318/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2020.583318/full

Similar Items