Nested pool testing strategy for the diagnosis of infectious diseases

Abstract The progress of the SARS-CoV-2 pandemic requires the design of large-scale, cost-effective testing programs. Pooling samples provides a solution if the tests are sensitive enough. In this regard, the use of the gold standard, RT-qPCR, raises some concerns. Recently, droplet digital PCR (ddP...

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Bibliographic Details
Main Authors: Inés Armendáriz, Pablo A. Ferrari, Daniel Fraiman, José M. Martínez, Hugo G. Menzella, Silvina Ponce Dawson
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97534-7