Myeloperoxidase Inhibitory and Antioxidant Activities of (<i>E</i>)-2-Hydroxy-α-aminocinnamic Acids Obtained through Microwave-Assisted Synthesis

Myeloperoxidase Inhibitory and Antioxidant Activities of (<i>E</i>)-2-Hydroxy-α-aminocinnamic Acids Obtained through Microwave-Assisted Synthesis

Myeloperoxidase (MPO) is an enzyme present in human neutrophils, whose main role is to provide defenses against invading pathogens. However, highly reactive oxygen species (ROS), such as HOCl, are generated from MPO activity, leading to chronic diseases. Herein, we report the microwave-assisted synt...

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Bibliographic Details
Main Authors: Astrid Rivera-Antonio, Martha Cecilia Rosales-Hernández, Irving Balbuena-Rebolledo, José Martín Santiago-Quintana, Jessica Elena Mendieta-Wejebe, José Correa-Basurto, Juan Benjamín García-Vázquez, Efrén Venancio García-Báez, Itzia I. Padilla-Martínez
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Pharmaceuticals
Subjects:
(<i>Z</i>)-2-hydroxycinnamic acid
(<i>E</i>)-dehydro-Phe
hypochlorous acid
antioxidants
3-acetamidocoumarins
3-aminocoumarins
Online Access:https://www.mdpi.com/1424-8247/14/6/513

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https://www.mdpi.com/1424-8247/14/6/513

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