Notch Signaling Enhances Nestin Expression in Gliomas

Recent findings suggest that Notch signaling is active in brain tumors and stem cells, and that stem cells or cells with progenitor characteristics contribute to brain tumor formation. These stem cells are marked by expression of several markers, including nestin, an intermediate filament protein....

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Bibliographic Details
Main Authors: Alan H. Shih, Eric C. Holland
Format: Article
Language:English
Published: Elsevier 2006-12-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558606801132