SOX10 transactivates S100B to suppress Schwann cell proliferation and to promote myelination.

SOX10 transactivates S100B to suppress Schwann cell proliferation and to promote myelination.

Schwann cells are an important cell source for regenerative therapy for neural disorders. We investigated the role of the transcription factor sex determining region Y (SRY)-box 10 (SOX10) in the proliferation and myelination of Schwann cells. SOX10 is predominantly expressed in rat sciatic nerve-de...

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Bibliographic Details
Main Authors: Sayaka Fujiwara, Shinya Hoshikawa, Takaaki Ueno, Makoto Hirata, Taku Saito, Toshiyuki Ikeda, Hiroshi Kawaguchi, Kozo Nakamura, Sakae Tanaka, Toru Ogata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4275212?pdf=render

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http://europepmc.org/articles/PMC4275212?pdf=render

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