Antitumor Effect of Cabozantinib in Bone Metastatic Models of Renal Cell Carcinoma

Background: The presence of bone metastases in renal cell carcinoma (RCC) negatively affects patients’ survival. Data from clinical trials has highlighted a significant benefit of cabozantinib in bone metastatic RCC patients. Here, we evaluated the antitumor effect of cabozantinib in coculture model...

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Bibliographic Details
Main Authors: Michele Iuliani, Sonia Simonetti, Francesco Pantano, Giulia Ribelli, Alberto Di Martino, Vincenzo Denaro, Bruno Vincenzi, Antonio Russo, Giuseppe Tonini, Daniele Santini
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/10/8/781