Vascular Inflammation Is a Risk Factor Associated with Brain Atrophy and Disease Severity in Parkinson’s Disease: A Case-Control Study

Introduction. Systemic inflammation with elevated oxidative stress causing neuroinflammation is considered a major factor in the pathogenesis of Parkinson’s disease (PD). The interface between systemic circulation and the brain parenchyma is the blood-brain barrier (BBB), which also plays a role in...

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Main Authors: Chiun-Chieh Yu, Hsiu-Ling Chen, Meng-Hsiang Chen, Cheng-Hsien Lu, Nai-Wen Tsai, Chih-Cheng Huang, Yung-Yee Chang, Shau-Hsuan Li, Yueh-Sheng Chen, Pi-Ling Chiang, Wei-Che Lin
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/2591248