Genetic contribution to mesenchymal stem cell dysfunction in systemic lupus erythematosus

Abstract Allogeneic mesenchymal stem cell (MSC) transplantation has recently become a promising therapy for patients with systemic lupus erythematosus (SLE). MSCs are a kind of multipotent stem cell than can efficiently modulate both innate and adaptive immune responses, yet those from SLE patients...

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Bibliographic Details
Main Authors: Yantong Zhu, Xuebing Feng
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-018-0898-x