Liver fluke granulin promotes extracellular vesicle-mediated crosstalk and cellular microenvironment conducive to cholangiocarcinoma

Liver fluke granulin promotes extracellular vesicle-mediated crosstalk and cellular microenvironment conducive to cholangiocarcinoma

Crosstalk between malignant and neighboring cells contributes to tumor growth. In East Asia, infection with the liver fluke is a major risk factor for cholangiocarcinoma (CCA). The liver fluke Opisthorchis viverrini secretes a growth factor termed liver fluke granulin, a homologue of the human progr...

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Bibliographic Details
Main Authors: Patpicha Arunsan, Apisit Chaidee, Christina J. Cochran, Victoria H. Mann, Toshihiko Tanno, Chutima Kumkhaek, Michael J. Smout, Shannon E. Karinshak, Rutchanee Rodpai, Javier Sotillo, Alex Loukas, Thewarach Laha, Paul J. Brindley, Wannaporn Ittiprasert
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558620300221

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http://www.sciencedirect.com/science/article/pii/S1476558620300221

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