Use of the γ-H2AX assay to investigate DNA repair dynamics following multiple radiation exposures.

Radiation therapy is one of the most common and effective strategies used to treat cancer. The irradiation is usually performed with a fractionated scheme, where the dose required to kill tumour cells is given in several sessions, spaced by specific time intervals, to allow healthy tissue recovery....

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Bibliographic Details
Main Authors: Luca G Mariotti, Giacomo Pirovano, Kienan I Savage, Mihaela Ghita, Andrea Ottolenghi, Kevin M Prise, Giuseppe Schettino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3843657?pdf=render