Human neutrophils depend on extrinsic factors produced by monocytes for their survival response to TLR4 stimulation

LPS delays neutrophil apoptosis by a process generally assumed to involve cell-intrinsic TLR4 signaling. However, neutrophil survival responses to LPS have been reported to be monocyte-dependent, which would indicate more complexity than is currently appreciated. We compared the survival responses o...

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Bibliographic Details
Main Authors: Shuvasree SenGupta, Madhavi J Rane, Silvia M Uriarte, Cassandra Woolley, Thomas C Mitchell
Format: Article
Language:English
Published: SAGE Publishing 2019-11-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/1753425919871994