Cerebrospinal fluid biomarkers for Alzheimer's and vascular disease vary by age, gender, and APOE genotype in cognitively normal adults

Cerebrospinal fluid biomarkers for Alzheimer's and vascular disease vary by age, gender, and APOE genotype in cognitively normal adults

Abstract Background This study sought to evaluate gender and APOE genotype-related differences in the concentrations of cerebrospinal fluid (CSF) biomarkers for Alzheimer’s disease (AD) and cerebrovascular injury across the life span of cognitively normal adults. Methods CSF amyloid beta1–42 (Aβ42),...

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Bibliographic Details
Main Authors: Ge Li, Jane B. Shofer, Eric C. Petrie, Chang-En Yu, Charles W. Wilkinson, Dianne P. Figlewicz, Andrew Shutes-David, Jing Zhang, Thomas J. Montine, Murray A. Raskind, Joseph F. Quinn, Douglas R. Galasko, Elaine R. Peskind
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Alzheimer’s disease
Cerebrovascular disease
Cerebrospinal fluid
Biomarkers
Age
Gender
Online Access:http://link.springer.com/article/10.1186/s13195-017-0271-9

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http://link.springer.com/article/10.1186/s13195-017-0271-9

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