HLA-G 3’UTR Polymorphisms Are Linked to Susceptibility and Survival in Spanish Gastric Adenocarcinoma Patients

HLA-G 3’UTR Polymorphisms Are Linked to Susceptibility and Survival in Spanish Gastric Adenocarcinoma Patients

HLA-G is a non-classical class I HLA molecule that induces tolerance by acting on receptors of both innate and adaptive immune cells. When overexpressed in tumors, limits surveillance by the immune system. The HLA-G gene shows several polymorphisms involved in mRNA and protein levels. We decided to...

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Bibliographic Details
Main Authors: Christian Vaquero-Yuste, Ignacio Juarez, Marta Molina-Alejandre, Elisa María Molanes-López, Adrián López-Nares, Fabio Suárez-Trujillo, Alberto Gutiérrez-Calvo, Adela López-García, Inmaculada Lasa, Remedios Gómez, Eduardo Fernández-Cruz, Carmen Rodrígez-Sainz, Antonio Arnaiz-Villena, José Manuel Martín-Villa
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
HLA-G
cancer
gastric cancer
immunotherapy
immunoediting
+3142 C/G
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.698438/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.698438/full

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