Insect-Specific Flavivirus Replication in Mammalian Cells Is Inhibited by Physiological Temperature and the Zinc-Finger Antiviral Protein

Insect-Specific Flavivirus Replication in Mammalian Cells Is Inhibited by Physiological Temperature and the Zinc-Finger Antiviral Protein

The genus <i>Flavivirus</i> contains pathogenic vertebrate-infecting flaviviruses (VIFs) and insect-specific flaviviruses (ISF). ISF transmission to vertebrates is inhibited at multiple stages of the cellular infection cycle, via yet to be elucidated specific antiviral responses. The zin...

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Bibliographic Details
Main Authors: Agathe M.G. Colmant, Jody Hobson-Peters, Teun A.P. Slijkerman, Jessica J. Harrison, Gorben P. Pijlman, Monique M. van Oers, Peter Simmonds, Roy A. Hall, Jelke J. Fros
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Viruses
Subjects:
insect-specific flavivirus
CpG
Dinucleotides
innate immunity
zinc-finger antiviral protein
Online Access:https://www.mdpi.com/1999-4915/13/4/573

Internet

https://www.mdpi.com/1999-4915/13/4/573

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