Safety and efficacy of adefovir therapy for lamivudine-resistant hepatitis B virus infection in renal transplant recipients

Safety and efficacy of adefovir therapy for lamivudine-resistant hepatitis B virus infection in renal transplant recipients

The emergence of lamivudine (LAM)-resistant mutants after prolonged LAM therapy may reduce its therapeutic effects against hepatitis B virus (HBV). Adefovir dipivoxil (ADV) is an effective treatment of LAM-resistant HBV infections. However, only limited data are available regarding the safety and ef...

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Bibliographic Details
Main Authors: Hsin-Wu Lai, Chiu-Chun Chang, Tan-Hsia Chen, Ming-Chang Tsai, Tzy-Yen Chen, Chun-Che Lin
Format: Article
Language:English
Published: Elsevier 2012-08-01
Series:Journal of the Formosan Medical Association
Subjects:
adefovir dipivoxil
hepatitis B surface antigen
lamivudine resistance
nephrotoxicity
renal transplant recipient
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664612000587

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http://www.sciencedirect.com/science/article/pii/S0929664612000587

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