Post-status epilepticus treatment with the Fyn inhibitor, saracatinib, improves cognitive function in mice

Post-status epilepticus treatment with the Fyn inhibitor, saracatinib, improves cognitive function in mice

Abstract Background Status epilepticus (SE) is a life-threatening neurological disorder. The hippocampus, as an important area of the brain that regulates cognitive function, is usually damaged after SE, and cognitive deficits often result from hippocampal neurons lost after SE. Fyn, a non-receptor...

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Bibliographic Details
Main Authors: Xin-Ming Luo, Jing Zhao, Wen-Yue Wu, Jie Fu, Zheng-Yu Li, Ming Zhang, Jie Lu
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Neuroscience
Subjects:
Status epilepticus
Fyn inhibitor
Saracatinib
Cognitive function
Hippocampal neurons
Online Access:https://doi.org/10.1186/s12868-020-00606-z

Internet

https://doi.org/10.1186/s12868-020-00606-z

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