Nobiletin suppresses monocyte chemoattractant protein-1 (MCP-1) expression by regulating MAPK signaling in 3T3-L1 cells

Nobiletin suppresses monocyte chemoattractant protein-1 (MCP-1) expression by regulating MAPK signaling in 3T3-L1 cells

Nobiletin is a major citrus flavonoid possessing several biological activities. Nobiletin has been reported to display anti-inflammatory activity and to reduce monocyte chemoattractant protein (MCP)-1 secretion by 3T3-L1 adipocytes. However, its mode of action remains unclear. In the present study,...

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Bibliographic Details
Main Authors: Sho Yasunaga, Miku Domen, Kosuke Nishi, Ayumu Kadota, Takuya Sugahara
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Journal of Functional Foods
Subjects:
Nobiletin
MCP-1
Chemokines
Adipocyte hypertrophy
3T3-L1 cells
Tumor necrosis factor α
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464616303036

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http://www.sciencedirect.com/science/article/pii/S1756464616303036

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