Exosomal delivery of therapeutic modulators through the blood–brain barrier; promise and pitfalls

Abstract Nowadays, a large population around the world, especially the elderly, suffers from neurological inflammatory and degenerative disorders/diseases. Current drug delivery strategies are facing different challenges because of the presence of the BBB, which limits the transport of various subst...

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Bibliographic Details
Main Authors: Morteza Heidarzadeh, Yasemin Gürsoy-Özdemir, Mehmet Kaya, Aysan Eslami Abriz, Amir Zarebkohan, Reza Rahbarghazi, Emel Sokullu
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-021-00650-0