RNA sequencing of intestinal mucosa reveals novel pathways functionally linked to celiac disease pathogenesis.

RNA sequencing of intestinal mucosa reveals novel pathways functionally linked to celiac disease pathogenesis.

<h4>Background & aims</h4>The early steps in the pathophysiology of celiac disease (CD) leading to loss of tolerance to gluten are poorly described. Our aim was to use RNA sequencing of duodenal biopsies in patients with active CD, CD in remission, and non-CD controls to gain insight...

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Main Authors: Maureen M Leonard, Yu Bai, Gloria Serena, Kourtney P Nickerson, Stephanie Camhi, Craig Sturgeon, Shu Yan, Maria R Fiorentino, Aubrey Katz, Barbara Nath, James Richter, Matthew Sleeman, Cagan Gurer, Alessio Fasano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0215132

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https://doi.org/10.1371/journal.pone.0215132

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