ALKBH5 promotes cadmium-induced transformation of human bronchial epithelial cells by regulating PTEN expression in an m6A-dependent manner

Cadmium is a carcinogenic heavy metal that poses a severe threat to human beings. The underlying mechanism, however, remains elusive. N6-methyladenosine (m6A) is the most abundant post-transcriptional modification in mRNA that regulates RNA metabolism. Emerging evidence shows that m6A is involved in...

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Bibliographic Details
Main Authors: Luyao Li, Mei Zhou, Biyun Chen, Qin Wang, Shuya Pan, Yaxuan Hou, Jiamin Xia, Xue Zhou
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321007983