Nanopattern surface improves cultured human myotube maturation

Abstract Background In vitro maturation of human primary myoblasts using 2D culture remains a challenging process and leads to immature fibers with poor internal organization and function. This would however represent a valuable system to study muscle physiology or pathophysiology from patient myobl...

Full description

Bibliographic Details
Main Authors: Jessica Brunetti, Stéphane Koenig, Arthur Monnier, Maud Frieden
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Skeletal Muscle
Subjects:
Online Access:https://doi.org/10.1186/s13395-021-00268-3